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Lupus Overlap Diseases


If you are newly diagnosed you may have heard the term “lupus overlap disease” mentioned by your doctor or another medical professional. If you have wondered what a “lupus overlap disease” means, what their possible symptoms are, causes, and treatments … you have come to the right place.


A lupus overlap disease is a disorder or disease that occurs in conjunction with your lupus. Although lupus can occur alone, many people with lupus experience an onset of one or more other connective tissue diseases. In these instances, a physician may use the term “overlap” to describe the illness. It has been found that people who have autoimmune diseases (that is when your body’s own defense system, your immune system, attacks your healthy cells by mistake) are more prone to develop other autoimmune diseases. As I have mentioned before, autoimmune diseases like to party together and often show up at your door like uninvited party guests.


Some of The most common diseases that overlap with lupus:

  • Antiphospholipid syndrome

  • Rheumatoid arthritis

  • Fibromyalgia

  • Sjogren's Syndrome

  • Raynaud's Syndrome

  • Mixed Connective Tissue Disease

  • Scleroderma